Serotonin May Perpetuate Chronic Pain - National Pain Report
http://bit.ly/1aRnuOh
http://americannewsreport.com/nationalpainreport/serotonin-may-perpetuate-chronic-pain-8822871.html
http://bit.ly/1aRnuOh
http://americannewsreport.com/nationalpainreport/serotonin-may-perpetuate-chronic-pain-8822871.html
Anyone who has read Dr. Forest Tennant's Intractable Pain Patients' Handbook for Survival or Overcoming Opiophobia knows that, contrary to popular belief, opioid pain medications do not cause pain and doctors are lying or ignorant if they tell you that they do. Unfortunately, opioids are all too frequently blamed for chronic pain. Yes, there are a handful of people who experience an increase in pre-existing pain from truly high doses of opioids. These incredibly rare cases have very specific diagnostic criteria and simply still being in pain on opioids doesn't indicate OIH, especially without a worsening of pain with each dose increase. This is seen as a tool to convince CP/IP patients and their caregivers to "free" the CP/IP patients from the treatments that actually relieve pain (mu-opioids & methadone).
"No magic bullet. The worst propaganda being pushed upon all chronic pain patients, including those with and without intractable pain are the illusive "magic bullet" formulas being advanced by either pharmaceutical and medical device industries, unethical practitioners and some health plans and government agencies...The worst deception these days is the fraudulent pitch that pain can be cured by stopping all medications, as if control is the cause!!"
-Forest Tennant MD PhD
-Forest Tennant MD PhD
...Here comes the irony... (sorry for the long preamble)
As it turns out, the medications that the OIH proponents prescribe and recommend most often (serotonin increasing antidepressants, like serious SSNRIs, MAOIs, TCAs, & atypical antidepressants, like Remeron/mirtazapine) could be what is actually worsening pain in chronic pain patients! Seriously! How's that for irony? Not only are these doctors manipulating their patients out of effective treatments, but they may actually be making their pain worse with these psychotropic medications (plenty of which are neurotoxic).
As it turns out, the medications that the OIH proponents prescribe and recommend most often (serotonin increasing antidepressants, like serious SSNRIs, MAOIs, TCAs, & atypical antidepressants, like Remeron/mirtazapine) could be what is actually worsening pain in chronic pain patients! Seriously! How's that for irony? Not only are these doctors manipulating their patients out of effective treatments, but they may actually be making their pain worse with these psychotropic medications (plenty of which are neurotoxic).
Remember, procedures and surgeries are high & ultra high (respectively) profit while doctors get paid NOTHING for writing prescriptions and controlled substances (especially CIIs, like opioids) require even more non-reimbursed time thanks to the overstepping DEA, overzealous prosecutors, strict regulations, and public backlash thanks to an extremely small percentage of hefty doctors who ran already illegal pull mills.
~~While I can understand hesitating to risk your medical license, freedom, career, home, and the hundreds of thousands of dollars that must be spent to defend the criminal charges (still lose medical license & career), it is completely unethical to manipulate a patient into believing a lie so that you can commit malpractice by unilaterally rejecting an entire treatment modality without reasonable cause. I've had several PMs tell me that opioids are my best and/or only option, but they don't personally prescribe. That's horrible, but at least they didn't lie to or attempt to manipulate me like the PMs at Hopkins & UPenn did (unfortunately, this behavior is on the rise and more than half of all PMs engage in this kind of inappropriate behavior)~~
Notes:
* The only non-serotonin antidepressant is buproprion/Wellbutrin/Budeprion
* There is one antidepressant that actually enhanced serotonin reuptake (gets rid of the old, useless serotonin), however the FDA has not approved it (likely to avoid pissing off the multibillion dollar pro-serotonin antidepressant industry). For those of you outside the USA, the only commercially SSRE (Selective Serotonin Reuptake Enhancer) is called tianeptine/Stablon/Coaxil/Tatinol
* The National Pain Report article is based on a medical journal article in Neuron named "Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain"
http://www.cell.com/neuron/retrieve/pii/S0896627313011410
http://bit.ly/1aRrRbU
* If anyone reading this believes that they may have OIH (or knows anyone who believes that they have OIH), PLEASE email me! I'd greatly appreciate the chance to discuss it with you. If you're interested, I'll also provide you with information to help you determine if you actually have OIH.
* The only non-serotonin antidepressant is buproprion/Wellbutrin/Budeprion
* There is one antidepressant that actually enhanced serotonin reuptake (gets rid of the old, useless serotonin), however the FDA has not approved it (likely to avoid pissing off the multibillion dollar pro-serotonin antidepressant industry). For those of you outside the USA, the only commercially SSRE (Selective Serotonin Reuptake Enhancer) is called tianeptine/Stablon/Coaxil/Tatinol
* The National Pain Report article is based on a medical journal article in Neuron named "Central Terminal Sensitization of TRPV1 by Descending Serotonergic Facilitation Modulates Chronic Pain"
http://www.cell.com/neuron/retrieve/pii/S0896627313011410
http://bit.ly/1aRrRbU
* If anyone reading this believes that they may have OIH (or knows anyone who believes that they have OIH), PLEASE email me! I'd greatly appreciate the chance to discuss it with you. If you're interested, I'll also provide you with information to help you determine if you actually have OIH.
